MicroRNA 29 Targets Nuclear Factor-κB–Repressing Factor and Claudin 1 to Increase Intestinal Permeability
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چکیده
منابع مشابه
Nuclear factor (NF)-kB proteins: therapeutic targets*
N uclear factor (NF)-kB is a key player in the control of both innate and adaptive immunity. NF-kB proteins are present in the cytoplasm in association with inhibitory proteins called inhibitors of kB (IkBs). On activation by a large plethora of inducers, the IkB proteins are phosphorylated, ubiquitinated, and subsequently degraded in the proteasomes. Degradation of IkBs allows translocation of...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 2015
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2014.09.037